JAG1 anticorps

N° du produit ABIN2664595

L’anticorps Hamster arménien Monoclonal anti-JAG1 a été validé pour IHC, FACS et IF. Il convient pour détecter JAG1 dans des échantillons de Souris.

Aperçu rapide pour JAG1 anticorps (ABIN2664595)

Antigène: JAG1 (Jagged 1 (JAG1))

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp JAG1 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: HMJ1-29

Détail du produit anti-JAG1 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur JAG1

Antigène: JAG1 (Jagged 1 (JAG1))

Autre désignation: CD339

Sujet: CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.

Pathways: Signalisation Notch, Stem Cell Maintenance